Pulloxhill is situated about 5 miles north-east of junction 12 of the M1. It is immediately to the west of the A6 about halfway between Luton and Bedford.
The nearest railway station is at Flitwick, about three miles from Pulloxhill. From there, trains are operated by First Capital Connect on the Bedford to Brighton line. This includes stops at Luton Airport (15 minutes), London St Pancras (50 minutes), other London stations and Gatwick airport (1 hour 40 minutes).
Pulloxhill is served by two commercial bus companies.
Grant Palmer operates a service through Toddington, Flitwick and Hitchen (number 77).
Centrebus operates a service to and from Luton (number 20).
In addition, the Flittabus runs services to Milton Keynes, Ampthill, Flitwick and other local villages on single days of the week. Flittabus is a voluntary organisation, staffed entirely by volunteers. Timetables can be obtained via the Central bedfordshire website.
The nearest airport is Luton, which is easily accessible by both road and rail.